Antibody-Binding Proteins and Conjugates
Cayman Chemical D-LucIferInpotasIum salt 500mg
An inhibitor of GVIA iPLA2 inhibits GVIA iPLA2 by 99.9 at 0.091 mol fraction in a mixed micelle activity assay is selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows 80.8 and 36.8 inhibition respectively inhibits iPLA2B activity in cytosolic extracts from INS-1 cells overexpressing iPLA2B (IC50 ~50 nM) as well as iPLA2Y activity in mouse heart membrane fractions (IC50 ~1-3 M) inhibits glucose-induced increases in PGE2 production and insulin secretion in human pancreatic islets at 10 M inhibits thapsigargin-induced apoptosis in INS-1 cells overexpressing iPLA2B in a concentration-dependent manner reduces blood glucose levels in an intraperitoneal glucose tolerance test and incidence of diabetes and increases serum insulin levels in NOD mice at 20 mg/kg 3 times per week
Cayman Chemical D-LucIferInpotasIum salt 50mg
Immunogen Synthetic peptide from the N-terminal region of human NF-KB (p65) Host Rabbit Species Reactivity ( ) Human chimpanzee monkey Applications WB MW 60 kDa
Cayman Chemical TInptInsodIum salt 50mg
A piperazine derivative with cardioprotective activity reduces INa in mouse myocytes expressing the long QT syndrome 3 mutant sodium channel DKPQ ventricular myocytes isolated from a canine model of heart failure guinea pig ventricular myocytes exposed to hydrogen peroxide or anemone toxin-II and HEK293 cells expressing human Nav1.5 channels (IC50s 5.9-15 M) reduces IKr in canine ventricular myocytes and HEK293 cells (IC50s 11.5 and 14.4 M respectively) reduces clofilium-induced prolongation of the QTc interval and TdP in rabbits at 480 g/kg per min reduces interstitial collagen deposition as well as ANP CTGF BNP and MMP-2 mRNA levels and prevents left ventricular dilation in a mouse model of doxorubicin-induced cardiotoxicity
Cayman Chemical PPAdodIum salt 50mg
An RXR agonist (EC50s 28 25 and 20 nM for RXRa RXRB and RXRY respectively in reporter assays) selective for RXRs over RARs (RARs EC50s 10 UM for RXRa RXRB and RXRY) induces apoptosis in MJ HuT 78 and HH CTCL cells at 10 UM inhibits lung metastasis and angiogenesis in A549 and MDA-MB-231 mouse xenograft models at 100 mg/kg per day reduces viral load in the culture supernatant of Vero E6 cells infected with SARS-CoV-2 (EC90 9.4 UM) and inhibits SARS-CoV-2 replication in a plaque reduction assay (EC50 2.01 UM)
Fluidigm Corp ANTI-MO/HU CD44 -171YB
CD44, also known as Hermes, Pgp-1, H-CAM, and HUTCH, is a cell surface glycoprotein. It is involved in a variety of cellular functions including: cell-to-cell interactions, adhesion, homing, and migration and is a receptor for haluronic acid. CD44 is expressed on a number of cell types including leukocytes, endothilial cells, hepatocytes, and mesenchymal cells and has been reported to be a marker for memory cell subsets.
Revvity Health Sciences Inc AlphaLISA Anti-Rabbit IgG-Fc Acceptor Beads, 5 mg
AlphaLISA Anti-Rabbit IgG-Fc Acceptor Beads, 5 mg
Cayman Chemical FuregrelatesodIum salt 50mg
A synthetic intermediate has been used as an intermediate in the synthesis of semaglutide as well as a lipid side chain to increase the proteolysis-resistance of insulin derivatives for use in vivo
Revvity Health Sciences Inc LANCE Ultra Anti-Phospho-IκBα (Ser32/36) Eu-Antibody, 10 µg
LANCE Ultra Anti-Phospho-IκBα (Ser32/36) Eu-Antibody, 10 µg
Revvity Health Sciences Inc LANCE Ultra Anti-Phospho-MBP (Thr232) Eu-Antibody, 100 µg
LANCE Ultra Anti-Phospho-MBP (Thr232) Eu-Antibody, 100 µg
Revvity Health Sciences Inc AlphaLISA Anti-GST Acceptor Beads, 5 mg
AlphaLISA Anti-GST Acceptor Beads, 5 mg
Revvity Health Sciences Inc LANCE Ultra Anti-methyl-Arg Eu-Antibody, 100 µg
LANCE Ultra Anti-methyl-Arg Eu-Antibody, 100 µg
Revvity Health Sciences Inc AlphaLISA Anti-unmodified Histone H3 Lysine 4 (H3K4) Acceptor Beads, 250 ug
AlphaLISA Anti-unmodified Histone H3 Lysine 4 (H3K4) Acceptor Beads, 250 ug